It’s true, Brahmans are different—in about four million ways, as a team of Australian scientists have found after sequencing the genome of a popular Brahman bull.
The genetic map of the Bos indicus Brahman now joins the genomic map of the tropically adapted Bos taurus Tuli and Africander bulls—also sequenced by Australian researchers—to provide the first genetic picture of what makes tropically-adapted breeds different from their temperate cousins.
In the case of the Brahman, the sequencing identified that the breed has more than four million variations in its DNA compared to the DNA of temperate cattle breeds.
That means four million points of difference that scientists can use to identify valuable production traits to be bred into future Brahman cattle and other tropically-adapted breeds.
“It’s critical Australian producers can use DNA markers that incorporate the genetic variation that occurs in tropically adapted cattle – over half of Australia’s beef production is based in the tropics,” said Beef CRC chief executive officer Dr Heather Burrow.
“To date, most of the data used to make DNA markers have been based on breeds which are suited to a temperate climate.”
Gene sequencing maps the order of the four molecules that are the basis of DNA. The molecules occur in infinitely variable chains, with subtle variations giving rise to the differences between different breeds and races of the same animal.
The information gleaned from genome sequencing will be compiled on chips containing Single Nucleotide Polymorphism information—”SNP chips”.
Each SNP chip carries selected DNA sequences that allow researchers to distinguish the genes of one animal from another.
In the early days of the Beef CRC, it was thought that a handful of genes would explain traits like tenderness, feed efficiency or reproductive performance. Through laborious efforts, some of those genes were identified.
It is now understood that each trait may be influenced by hundreds, thousands or even tens of thousands of genes.
Technology has taken quantum leaps since Beef CRC I. Today’s SNP chips can carry at least half a million variations in DNA sequences between animals and across breeds, providing a rapid means of assessing where ariations occur.
Researchers can use this information to develop genetic improvement tools such as DNA marker panels to predict animals that will perform best in particular environments, and for particular markets.
Producers can use these genetic tools to select animals for breeding purposes, or to manage animals to better meet the specifications of premium beef markets.
Mapping the Brahman genome will also help researchers identify “what makes a Brahman a Brahman”, according to gene marker pioneer Dr Bill Barendse of CSIRO Livestock Industries.
Most of the bovine gene mapping that has been done overseas has focused on the Hereford and dairy breeds.
The Australian bovine sequencing team, a joint venture between the Beef CRC, CSIRO Livestock Industries, and Victorian Department of Primary Industries, have focused on the tropically-adapted breeds because of their importance to the Australian beef economy.
No other developed country places as much importance on tropical adaptation in its beef cattle. Brahman and Brahman-cross cattle comprise over half of Australian beef cattle population, and over the past 40 years are estimated to have contributed more than $10 billion to the Australian beef industry.
The Brahman bull whose genome was sequenced was chosen because he has been widely used in the northern cattle industry, providing a benchmark that can be used in future research to assess genetic variation.
The bull’s identity will not be revealed for commercial reasons.